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Research & Innovation

Research at SLC

 

Sheba Longevity encompasses utilizing data science and AI techniques to analyze complex datasets, conduct clinical trials to evaluate longevity therapeutics, study biomarkers of healthy longevity, explore fundamental biological mechanisms, and translate laboratory findings into practical healthcare applications.

Currently Recruiting

The SHARP study - Sheba Healthspan Research Population trial
The SHARP study - Sheba Healthspan Research Population trial

We are currently conducting a randomized control study among healthy adults to assess the effect of a personalized health and behavior intervention program based on a multi model analysis system and diagnostic of multidimensional performance domains. 

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Research Fields

Data science & AI
Data science & AI
Data science & AI
Clinical trials
Clinical trials
Clinical trials
Basic Science
Basic Science
Basic Science
Translational Research
Translational Research
Translational Research

Ongoing Research

Biological age, mortality and hospitalization rate

Leading PI: Dr. Abigail Goshen, Prof Tzipi Strauss

 
Melatonin and circadian rhythms in aging & hypertension

Leading PI: Dr. Avshalom Leibowitz

 
Environmental exposures affecting menopausal timing and symptoms

Leading PI: Dr.Lauren Petrick

 
Validating an Israeli Frailty Index score

Leading PI: Dr. Abigail Goshen, Prof Tzipi Strauss

 
Voice recognition and CV risk

Leading PI: Dr. Elad Maor

 
Developing predictive models based on metabolite profiles to identify individuals at high risk of developing CVD

Leading PI: Dr. Michael Elgart and Dr. Abigail Goshen

 
The Gut Microbiome and Cognitive Performance longitudinal study

Leading PI: Prof. Tzipi Strauss , Prof. Eran Elinav, Dr Abigail Goshen
Utilizing DELPHI test results for Early Detection and Predictive ability of mild cognitive decline and physical frailty

Leading PI: Dr. Abigail Goshen

Publications

Longevity medicine: upskilling the physicians of tomorrow
The Lancet
|
March 12, 2021
Longevity Medicine: Upskilling the Physicians of Tomorrow

Evelyne Bischof, Morten Scheibye-Knudsen*, Richard Siow, Alexey Moskalev

קרא עוד
Artifcial intelligence in longevity medicine
Nature Aging
|
January 1, 2021
Artifcial Intelligence in Longevity Medicine

Alex Zhavoronkov, Evelyne Bischof and Kai-Fu Lee

קרא עוד
Advanced Pathological Ageing Should be Represented in the ICD
The Lancet
|
January 1, 2022
Advanced Pathological Ageing Should be Represented in the ICD

Evelyne Bischof, Andrea B Maier, Kai-Fu Lee, Alex Zhavoronkov, *David Sinclair

קרא עוד
Association of Diet Quality With Longevity and Successful Aging in Israeli Adults 65 Years or Older
JAMA Network Open
|
June 1, 2022
Association of Diet Quality With Longevity and Successful Aging in Israeli Adults 65 Years or Older

Abigail Goshen, MSc; Uri Goldbourt, PhD; Yael Benyamini, PhD; Tal Shimony, MSc; Lital Keinan-Boker, MD, PhD; Yariv Gerber, PhD

קרא עוד
Diet Quality and Incident Frailty in Adults 65 Years or Older: The Israeli Longitudinal Study on Aging - ScienceDirect.
Mayo Clinic Proceedings
|
December 1, 2023
Diet Quality and Incident Frailty in Adults 65 Years or Older: The Israeli Longitudinal Study on Aging - ScienceDirect

Abigail Goshen PhD, Uri Goldbourt PhD, Yael Benyamini PhD, Tal Shimony MSc, Lital Keinan-Boker MD, PhD, Yariv Gerber PhD

קרא עוד
Establishing healthy longevity clinics in publicly funded hospitals
GeroScience
|
March 21, 2024
Establishing healthy longevity clinics in publicly funded hospitals

Tzipora Strauss , Sara L. R. Bonnes, Allyson K. Palmer, Ryan T. Hurt, Louis Island, Abigail Goshen, Laureen Y. T. Wang, James L. Kirkland, Evelyne Bischof & Andrea B. Maier

קרא עוד